Investigator-Sponsored Trials / Research (IST / ISR)
Collaborations with scientists and clinicians outside of 4SC are important for us in delivering our epigenetic drugs to patients in indications with high unmet medical need.
Therefore, we welcome proposals from academia and biotech or pharma companies ranging from preclinical research projects to investigator-sponsored clinical collaborations at any time. We offer a straightforward scientist-to-scientist approach and project evaluations with a rapid turnaround time.
Our main interests are:
- Biology and (patho-) physiology of histone deacetylases (HDACs) and epigenetic signaling pathways
- Clinical relevance of histone deacetylase (HDAC) inhibition, especially in solid tumors but also hematologic diseases, either as monotherapy or in combination approaches